基本信息
姓名：燕双仟
籍贯：湖南常德
学位：工学博士
职称：闽江学者特聘教授 博士生导师
研究方向：免疫治疗、纳米医学、微流控芯片
联系方式
办公地点：福建省福州市闽侯县上街镇福建师范大学旗山校区350117
电子邮箱：ifeshqyan@fjnu.edu.cn
教育背景
2012.9 -- 2013.6 华中科技大学 化学学院 分析化学 硕士 导师：吴康兵教授
2013.9 -- 2017.6 华中科技大学 武汉光电国家实验室 生物医学工程 博士 导师：刘笔锋教授
工作经历
2017.12—2021.02 新加坡国立大学 化学院 Research Fellow 合作导师：刘小钢教授
2021.3--至今 福建师范大学 海峡柔性电子研究院 教授
获奖情况
闽江学者特聘教授（2021年）
承担项目情况
国家自然科学基金面上项目（2023-2026）
福建省自然科学基金青年项目（2021-2024）
福建省闽江学者人才项目（2021）
学术成果
主要从事疾病早期诊断及肿瘤诊疗微纳米制剂的研究，包括多功能微流控检测芯片、肿瘤微环境响应的纳米载体、功能化药物输送载体及影像诊断引导下的肿瘤免疫治疗制剂等。截止目前，已在Adv. Mater.、Angew. Chem. Int. Ed.、ACS Nano及Adv. Sci.等领域内著名期刊发表 SCI 论文 40余篇。
(1) Panpan Xue, Huilan Zhuang, Sijie Shao, Tingjie Bai, Xuemei Zeng*, Shuangqian Yan*, Engineering Biodegradable Hollow Silica/Iron Composite Nanozymes for Breast Tumor Treatment through Activation of the “Ferroptosis Storm”, ACS Nano, 2024, 18, 25795-25812
(2) Tingjie Bai#, Panpan Xue#, Sijie Shao, Shuangqian Yan*, and Xuemei Zeng*, Cholesterol Depletion-Enhanced Ferroptosis and Immunotherapy via Engineered Nanozyme, Advanced Science, 2024, 2405826
(3) Huilan Zhuang#, Lun Wang#, Sijie Shao, Haitong Jing, Panpan Xue, Tingjie Bai, Jinpeng Deng, Xuemei Zeng*, Xian Qin*, Shuangqian Yan*, Photocatalysis-promoted tumor ferroptosis enabled by MOF-derived black TiO2, Chemical Engineering Journal, 2024, 154204
(4) Panpan Xue, Huilan Zhuang, Tingjie Bai, Xuemei Zeng*, Jinpeng Deng, Sijie Shao, Shuangqian Yan*, Iron (II)-based metal-organic framework nanozyme for boosting tumor ferroptosis through inhibiting DNA damage repair and system Xc-, Journal of Nanobiotechnology, 2024, 22:228
(5) Jinpeng Deng, Huilan Zhuang, Sijie Shao, Xuemei Zeng*, Panpan Xue, Tingjie Bai, Xiaoman Wang, Shijie Shangguan, Yuanchun Chen, Shuangqian Yan*, Wei Huang*, Mitochondrial-Targeted Copper Delivery for Cuproptosis-Based Synergistic Cancer Therapy, Advanced Healthcare Materials, 2024, 13, 2304522
(6) Huilan Zhuang, Panpan Xue, Sijie Shao, Xuemei Zeng*, Shuangqian Yan*, In situ generation of hybrid alginate hydrogels for enhance breast tumor ferrotherapy through multiplex magnifying redox imbalances, International Journal of Biological Macromolecules, 2024, 258, 128952
(7) Yihang Ruan#, Huilan Zhuang#, Xuemei Zeng*, Lili Lin, Xuechun Wang, Panpan Xue, Shan Xu, Qi Chen*, Shuangqian Yan*, Wei Huang*, Engineered Microbial Nanohybrids for Tumor-Mediated NIR II Photothermal Enhanced Ferroptosis/Cuproptosis and Immunotherapy, Advanced Healthcare Materials, 2023, 2302537 (Title Page)
(8) Xuemei Zeng, Yihang Ruan, Qi Chen*, Shuangqian Yan*, Wei Huang*, Biocatalytic cascade in tumor microenvironment with a Fe2O3/Au hybrid nanozyme for synergistic treatment of triple negative breast cancer, Chemical Engineering Journal, 452, 2023, 138422
(9) Shuangqian Yan,* Xuemei Zeng, Yu Wang,* and Bi-Feng Liu*, Biomineralization of Bacteria by a Metal–Organic Framework for Therapeutic Delivery, Advanced Healthcare Materials, 2020, 2000046 (Cover)
(10) Shuangqian Yan, Zichao Luo, Zhenglin Li, Yu Wang, Jun Tao, Changyang Gong, an Xiaogang Liu*, Improving Cancer Immunotherapy Outcomes usin Biomaterials, Angewandte Chemie International Edition, 2020, 59, 17332-17343
(11) Shuangqian Yan, Xuemei Zeng, Yong’an Tang, Bi-Feng Liu,* Yu Wang, and Xiaogang Liu* Activating Antitumor Immunity and Antimetastatic Effect Through Polydopamine-Encapsulated Core–Shell Upconversion Nanoparticles, Advanced Materials, 2019, 1905825
常年招收博士后（与深圳大学合作），年薪35万元以上，欢迎积极向上，具有化学、材料、生物背景的博士联系咨询。
